Trifluoromethyl-Substituted Sulfonium Ylide: Rh-Catalyzed Carbenoid Addition to Trifluoromethylthioether

Sulfonium Carbenoid Ylide Trifluoromethylation
DOI: 10.1021/acs.orglett.5b01170 Publication Date: 2015-05-14T19:35:41Z
ABSTRACT
A highly efficient Rh-catalyzed carbenoid addition to trifluoromethylthioether for the formation of trifluoromethyl-substituted sulfonium ylide is described. The can act as an electrophilic trifluoromethylation reagent, demonstrated by β-ketoesters and aryl iodides.
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