(+)- and (−)-Pestaloxazine A, a Pair of Antiviral Enantiomeric Alkaloid Dimers with a Symmetric Spiro[oxazinane-piperazinedione] Skeleton from Pestalotiopsis sp.

• DOI: 10.1021/acs.orglett.5b01995
• Publication Date: 2015-08-20T17:46:07Z
• Authors: Yan-Lai Jia; Mei-Yan Wei; Hai-Yan Chen; Fei-Fei Guan; Chang-Yun Wang; Chang-Lun Shao
• Keywords: 0301 basic medicine; 0303 health sciences; Molecular Structure; Xylariales; Stereoisomerism; Antiviral Agents; 01 natural sciences; Piperazines; Enterovirus A, Human; 0104 chemical sciences; 3. Good health; 03 medical and health sciences; Alkaloids; Spiro Compounds; Nuclear Magnetic Resonance, Biomolecular; Chromatography, High Pressure Liquid

AbstractEnantiomer [(+)‐I] is shown to exhibit potent antiviral activity.