Approach to cis-Phlegmarine Alkaloids via Stereodivergent Reduction: Total Synthesis of (+)-Serratezomine E and Putative Structure of (−)-Huperzine N

• DOI: 10.1021/acs.orglett.5b02581
• Publication Date: 2015-09-25T18:24:07Z
• Authors: Caroline Bosch; Béla Fiser; Enrique Gómez-Bengoa; Ben Bradshaw; Josep Bonjoch
• Keywords: Compostos heterocíclics; Síntesi orgànica; Natural products; Molecular Structure; Organic synthesis; Stereoisomerism; Lycopodium; 01 natural sciences; Catalysis; 0104 chemical sciences; 3. Good health; Alkaloids; Alcaloides; Quinolines; Productes naturals; Heterocyclic compounds; Hydrogenation; Sesquiterpenes

AbstractBased on the executed total syntheses the structure of natural huperzine N is reassigned to (III), a diastereomer of (II).