A Hemimethyl-Substituted Cucurbit[7]uril Derived from 3α-Methyl-glycoluril

• DOI: 10.1021/acs.orglett.5b02588
• Publication Date: 2015-10-08T12:57:26Z
• Authors: Wen-Xuan Zhao; Chuan-Zeng Wang; Li-Xia Chen; Hang Cong; Xin Xiao; Yun-Qian Zhang; Sai-Feng Xue; Ying Huang; Zhu Tao; Qian-Jiang Zhu
• Keywords: Magnetic Resonance Spectroscopy; Molecular Structure; Alkynes; Imidazoles; Thermodynamics; Water; Dimethyl Sulfoxide; Crystallography, X-Ray; 01 natural sciences; 0104 chemical sciences; 3. Good health

A novel hemimethyl-substituted cucurbit[7]uril (HMeQ[7]) derived from 3α-methyl-glycoluril has been prepared. HMeQ[7] is readily soluble in both water and dimethyl sulfoxide (DMSO) and displays not only host-guest interaction properties similar to those of the normal cucurbit[7]uril but also unusual properties in DMSO.