Direct Allylic Amination of Allylic Alcohol Catalyzed by Palladium Complex Bearing Phosphine–Borane Ligand

• DOI: 10.1021/acs.orglett.7b03023
• Publication Date: 2017-11-02T21:58:58Z
• Authors: Goki Hirata; Hideaki Satomura; Hidenobu Kumagae; Aika Shimizu; Gen Onodera; Masanari Kimura
• Keywords: Boranes

The direct electrophilic, nucleophilic, and amphiphilic allylations of allylic alcohol by use a palladium catalyst organometallic reagents such as organoborane organozinc has been developed. phosphine–borane compound works the effective ligand for palladium-catalyzed amination alcohol. Thus, with secondary amines, reaction was completed in only 1 h, even at room temperature.