Construction of Benzene Rings by Copper-Catalyzed Cycloaddition Reactions of Oximes and Maleimides: An Access to Fused Phthalimides

• DOI: 10.1021/acs.orglett.8b00141
• Publication Date: 2018-02-07T14:26:28Z
• Authors: Jie Yang; Bo Zhao; Yue Xi; Si Sun; Zhen Yang; Ying Ye; Kun Jiang; Ye Wei
• Keywords: Phthalimides; Reaction conditions

A useful Cu-catalyzed cycloaddition protocol for the construction of benzene rings has been achieved. The reactions, utilizing readily available oximes and maleimides as starting materials, proceed under mild reaction conditions to generate a series structurally interesting fused-phthalimides that are difficult be prepared by conventional methods.