Eucalyptusdimers A–C, Dimeric Phloroglucinol–Phellandrene Meroterpenoids from Eucalyptus robusta
Phloroglucinol
Terpene
DOI:
10.1021/acs.orglett.8b02259
Publication Date:
2018-08-08T16:27:14Z
AUTHORS (9)
ABSTRACT
Eucalyptusdimers A-C, three dimeric phellandrene-derived meroterpenoids featuring an unprecedented, fused skeleton between two phellandrene and acylphloroglucinol subunits, along with one biogenetically related intermediate, (±)-eucalyprobusone A, were isolated from the fruits of Eucalyptus robusta. Their structures absolute configurations elucidated using spectroscopic data, X-ray crystallography, electronic circular dichroism analysis. The evaluated for their anti-inflammatory, acetylcholinesterase inhibitory, protein tyrosine phosphatase 1B inhibitory effects.
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