Tremella-Like ZnO@Col-I-Decorated Titanium Surfaces with Dual-Light-Defined Broad-Spectrum Antibacterial and Triple Osteogenic Properties

• DOI: 10.1021/acsami.0c05413
• Publication Date: 2020-06-17T17:25:30Z
• Authors: Siyu Zhao; Yingying Xu; Wenying Xu; Zhenzhen Weng; Fei Cao; Xinyi Wan; Tongcan Cui; Yajun Yu; Lan Liao; Xiaolei Wang
• Keywords: Surface Modification; Broad spectrum

The growing population of peri-implant diseases (PIDs) has become a public obsession, mainly due to the lack antibacterial ability and osteogenic promotion titanium (Ti) implants. Herein, inspired by tremella, we reported zinc oxide (ZnO)@collagen type I (Col-I)-decorated Ti for PIDs treatments. Compared with pure implants, ZnO@Col-I-decorated could be activated safe visible yellow light showed excellent broad-spectrum properties. proliferation gene expression bone marrow mesenchymal stem cells (BMSCs) indicated that triple osseointegration implants was realized through (I) remarkedly improved surface hydrophilicity Ti, (II) function Col-I, (III) near-infrared (NIR)-induced photothermal performance ZnO. Collectively, proposed dual-light-defined ZnO@Col-I coating promising implant modification system provide customized treatments each PID patient.