Selenium Vacancy Engineering Using Bi2Se3 Nanodots for Boosting Highly Efficient Photonic Hyperthermia
Nanomaterials
Nanodot
Photon Upconversion
DOI:
10.1021/acsami.1c13107
Publication Date:
2021-10-11T06:40:21Z
AUTHORS (8)
ABSTRACT
Despite bismuth-based energy conversion nanomaterials having attracted extensive attention for nanomedicine, the suffer from major shortcomings including low tumor accumulation, long internal retention time, and undesirable photothermal efficiency (PCE). To combat these challenges, bovine serum albumin folic acid co-modified Bi2Se3 nanomedicine with rich selenium vacancies (abbreviated as VSe-BS) was fabricated second near-infrared (NIR-II) light-triggered photonic hyperthermia. More importantly, on crystal planes (0 1 5) 11) of VSe-BS similar formation energies could be distinctively observed via aberration-corrected scanning transmission electron microscopy images. The defect engineering endows enhanced conductivity, making possess outstanding PCE (54.1%) in NIR-II biowindow desirable photoacoustic imaging performance. Tumor ablation studies indicate that possesses satisfactory therapeutic outcomes triggered by light. These findings give rise to inspiration further broadening biological applications nanomaterials.
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