Encapsulation of Gold Nanoparticles into Redesigned Ferritin Nanocages for the Assembly of Binary Superlattices Composed of Fluorophores and Gold Nanoparticles

• DOI: 10.1021/acsami.1c20520
• Publication Date: 2022-02-15T17:43:06Z
• Authors: Marcel Lach; Christian Strelow; Andreas Meyer; Alf Mews; Tobias Beck
• Keywords: Nanocages; Nanomaterials; Template; Nanoclusters

Nanomaterials with a defined composition and structure can be synthesized by exploiting natural templates or biomolecular matrices. In the present work, we use protein nanocages derived from human ferritin as nanoscale building block for assembly of gold nanoparticles fluorescent molecules in solid state. As generalizable strategy, show that prior to material synthesis, cargo encapsulated into using dis- reassembly approach. Toward this end, new ligand system enables efficient encapsulation these particles nanocages. The nanoparticle-loaded are co-assembled fluorophore-loaded Binary superlattices formed because two oppositely charged used assembly. binary crystals strong exciton-plasmon coupling between fluorophores nanoparticles, which was spatially resolved fluorescence lifetime imaging. strategy outlined here offers modular approach toward nanomaterials highly ordered blocks.