Molecularly Imprinted Polymer (MIP) Film with Improved Surface Area Developed by Using Metal–Organic Framework (MOF) for Sensitive Lipocalin (NGAL) Determination

• DOI: 10.1021/acsami.6b05515
• Publication Date: 2016-07-25T19:44:08Z
• Authors: Zofia Iskierko; Piyush Sindhu Sharma; Daniel Prochowicz; Krzysztof Fronc; Francis D’Souza; Diana Toczydłowska; Filip Stefaniak; Krzysztof Noworyta
• Keywords: Molecularly imprinted polymer

Electropolymerizable functional and cross-linking monomers were used to prepare conducting molecularly imprinted polymer film with improved surface area the help of a sacrificial metal-organic framework (MOF). Subsequent dissolution MOF layer resulted in developed MIP film. This enlargement increased analyte accessibility molecular cavities. Application porous as recognition unit an extended-gate field effect transistor (EG-FET) chemosensor effectively enhanced analytical current signals determination recombinant human neutrophil gelatinase-associated lipocalin (NGAL).