Silver Nanocluster-Embedded Zein Films as Antimicrobial Coating Materials for Food Packaging

• DOI: 10.1021/acsami.7b08152
• Publication Date: 2017-09-19T16:14:53Z
• Authors: Lei Mei; Zi Teng; Guizhi Zhu; Yijing Liu; Fuwu Zhang; Jinglin Zhang; Ying Li; Yongguang Guan; Yaguang Luo; Xianggui Chen; Qin Wang
• Keywords: Nanoclusters; Silver nanoparticle

Highly efficient antimicrobial agents with low toxicity and resistance have been enthusiastically pursued to address public concerns on microbial contamination in food. Silver nanoclusters (AgNCs) are known for their ultrasmall sizes unique optical chemical properties. Despite extensive studies of AgNCs biomedical applications, previous research application as antimicrobials food applications is very limited. Here, the first time, by incorporating (∼2 nm diameter) into zein films that widely used packaging materials, we developed a novel coating material potent activity, human cells, potential harm environment. In addition, systematically evaluated activities cytotoxicity AgNCs-embedded compared them embedded AgNO3 or Ag nanoparticles diameters 10 60 (AgNP10 AgNP60, respectively). At equivalent silver concentrations, solutions exhibited considerably higher than those AgNP10 AgNP60 solutions. Moreover, less cells AgNO3, half maximal inhibitory concentration (IC50) 34.68 μg/mL AgNCs, 9.14 AgNO3. Overall, this has great materials due its high efficacy, size, cytotoxicity.