Ratiometric Electrochemical Sensors Associated with Self-Cleaning Electrodes for Simultaneous Detection of Adrenaline, Serotonin, and Tryptophan

• DOI: 10.1021/acsami.8b22572
• Publication Date: 2019-03-15T11:45:48Z
• Authors: Junjie Zhang; Dongyang Wang; Yingchun Li
• Keywords: Polydimethylsiloxane; Electrochemical gas sensor

Electrochemical sensors have long suffered from issues such as nonspecific adsorption, poor anti-interference ability, and internal external disturbances. To address these challenges, we developed a facile electrochemical method, which integrated ratiometric strategy with self-cleaning electrodes. In the novel sensing system, electrode was realized via forming hydrophobic layer on carbonized ZIF-67@ZIF-8 (cZIF) by polydimethylsiloxane (PDMS) precursor vaporization. As for ratiometry, it is worth to mention that measurements were conducted adding an interior reference (methylene blue) directly into electrolyte solution, more flexible operate compared conventional ones. Sensing performance of well newly established explored fully, turned out PDMS@cZIF nanocomposites provided decent electrocatalytic superhydrophobic property, stability. Furthermore, significantly elevated robustness reproducibility sensing. Simultaneous detection Adr, 5-HT, Trp performed under optimum experimental conditions wide linear ranges low limits. Finally, original sensor successfully applied monitoring three target molecules in biological samples.