Study of Hepatic Dysfunction Associated with Dengue Epidemiology in a Tertiary Care Hospital, Kolkata

• DOI: 10.1021/acsomega.2c07119
• Publication Date: 2023-02-10T06:56:51Z
• Authors: Shreemoyee Palmal; Shruti Chakraborty; Swagata Ganguly; Suman Kundu; Jayanta Bikash Dey; Kaushik Pramanik; Arup Kumar Pattan...
• Keywords: Aspartate transaminase; Viral Hepatitis

Dengue is a common arthropod-borne life-threatening febrile illness. This disease affects liver functions with an imbalance of enzymes followed by other clinical manifestations. The dengue serotypes can cause asymptomatic infection to more severe versions hemorrhagic fever and shock syndrome in West Bengal around the globe. main aim this study establish how different act identifying markers for prognosis early detection (DF). diagnosis patients was confirmed enzyme-linked immunosorbent assay, associated parameters [aspartate transaminase (AST), alanine aminotransferase (ALT), alkaline phosphatase, total bilirubin, albumin, protein, packed cell volume, platelet count] were analyzed. Furthermore, viral load estimation also carried out RT PCR analysis. majority these had elevated AST ALT levels; levels higher than levels, which partially observed all non-structural protein 1 antigen- immunoglobulin M antibody-reactive patients. Almost 25% very low count or thrombocytopenia. shows significant association p-value <0.0001. All are significantly correlated increased level T.BIL, ALT, AST. depicts that intensity hepatic involvement may play critical role morbidity mortality DF As result, be useful determining severity disease, allowing high-risk cases.