Photo-Controllable DNA Origami Nanostructures Assembling into Predesigned Multiorientational Patterns

• DOI: 10.1021/ja307785r
• Publication Date: 2012-12-04T20:54:31Z
• Authors: Yangyang Yang; Masayuki Endo; Kumi Hidaka; Hiroshi Sugiyama
• Keywords: DNA origami; DNA nanotechnology; Template

We demonstrate a novel strategy for constructing multidirectional programmed 2D DNA nanostructures in various unique patterns by introducing photoresponsive oligonucleotides (Azo-ODNs) into hexagonal origami structures. examined regulation of assembly and disassembly reversibly different photoirradiation conditions manner. Azo-ODNs were incorporated to the structures, which then employed as self-assembly units building up nanosized architectures regulated arrangements. By adjusting numbers positions units, specific with face controlling can be achieved, resulting construction ring-shaped nanostructures. combining photoregulating system, remote has been accomplished simply photo irradiation.