Catalytic, Asymmetric, and Stereodivergent Synthesis of Non-Symmetric β,β-Diaryl-α-Amino Acids

• DOI: 10.1021/ja511872a
• Publication Date: 2014-12-19T01:40:21Z
• Authors: Carmela Molinaro; Jeremy P. Scott; Michael Shevlin; Christopher Wise; Alain Ménard; Andrew Gibb; Ellyn M. Junker; David Lieberman
• Keywords: Models, Molecular; Molecular Conformation; Stereoisomerism; Chemistry Techniques, Synthetic; 01 natural sciences; Catalysis; Substrate Specificity; 0104 chemical sciences; Hydrogenation; Amino Acids

AbstractStereodefined enol tosylates such as (III) and (VI) are prepared and subjected to a stereoretentive Suzuki—Miyaura coupling.