Self-Sorted, Random, and Block Supramolecular Copolymers via Sequence Controlled, Multicomponent Self-Assembly

• DOI: 10.1021/jacs.0c01822
• Publication Date: 2020-04-01T19:54:20Z
• Authors: Aritra Sarkar; Ranjan Sasmal; Charly Empereur-mot; Davide Bochicchio; Srinath V. K. Kom...; Kamna Sharma; Shikha Dhiman; Balasubramanian S...; Sarit S. Agasti; Giovanni M. Pavan; Subi J. George
• Keywords: Supramolecular Polymers; Sequence (biology); Supramolecular assembly

Multicomponent supramolecular copolymerization promises to construct complex nanostructures with emergent properties. However, even two monomeric components, various possible outcomes such as self-sorted homopolymers, a random (statistical) copolymer, an alternate or block copolymer can occur, determined by their intermolecular interactions and monomer exchange dynamics hence structural prediction is extremely challenging. Herein, we target this challenge demonstrate unprecedented two-component sequence controlled manipulating thermodynamic kinetic routes in the pathway complexity of self-assembly constitutive monomers. Extensive molecular simulations provided useful mechanistic insights into rates free energy between monomers that dictate sequence. The fluorescent nature core-substituted naphthalene diimide has been further utilized characterize three sequences via Structured Illumination Microscopy (SIM).