Specific Discrimination Polymerization for Highly Isotactic Polyesters Synthesis

• DOI: 10.1021/jacs.3c14091
• Publication Date: 2024-03-01T22:00:45Z
• Authors: Xuanhua Guo; Guangqiang Xu; Rulin Yang; Qinggang Wang
• Keywords: Tacticity; Kinetic resolution

Isotactic polymers have emerged with unique and excellent properties in material sciences. Specific discrimination polymerization provides an ideal pathway to achieve highly isotactic from their racemic monomers, which is of great significance a challenge polymeric chemistry. Although enantioselective catalyst-mediated asymmetric kinetic resolution (AKRP) process makes it possible, general well-defined strategy for catalyst design still rarely reported. Here, based on novel dual-ligand strategy, new type chiral (BisSalen)Al complex high enantioselectivity has been described, perfect AKRP phenethylglycolide (Pegl) achieved the first time. The more confined microenvironment formed by dual ligand key improve original catalyst. To illustrate generality this series complexes homo- or heterodual ligands were designed Pegl.