Adenosine-Phosphate-Fueled, Temporally Programmed Supramolecular Polymers with Multiple Transient States

• DOI: 10.1021/jacs.7b07469
• Publication Date: 2017-08-28T09:33:06Z
• Authors: Shikha Dhiman; Ankit Jain; Mohit Kumar; Subi J. George
• Keywords: 02 engineering and technology; 0210 nano-technology

Natural systems have been an inspiration to synthetic supramolecular chemistry. Synthetic demonstrations of dissipative biological systems such as actin filaments are a formidable scientific challenge in attaining future life-like materials. Dynamic instability of such structures beckons control of self-organization in the temporal regimes. In this study, we present a fuel-dependent helical assembly of a supramolecular polymer. We further attempt the synthetic manifestation of a temporally programmable self-assembly. Additionally, the fuel-induced chiral (re)organization with the employment of various enzymes singularly and in tandem have resulted in designing a multistate transient self-assembly. These parameter modulations result in controllable lifetimes and rates. We thus report, for the first time, a temporally programmed multistate reorganization of self-assembly.