An Organometallic Strategy for Assembling Atomically Precise Hybrid Nanomaterials

• DOI: 10.1021/jacs.9b10770
• Publication Date: 2019-11-29T23:54:11Z
• Authors: Julia M. Stauber; Elaine A. Qian; Yanxiao Han; Arnold L. Rheingold; Petr Král; Daishi Fujita; Alexander M. Spok...
• Keywords: Nanoclusters; Nanomaterials; Surface Modification

For decades, chemists have strived to mimic the intricate design and diverse functions of naturally occurring systems through bioinspired synthesis programmable inorganic nanomaterials. The development thiol-capped gold nanoparticles (AuNPs) has driven advancement in this area; however, although versatile readily accessible, hybrid AuNPs are rarely atomically precise, which limits control over their surface topology therefore study complex structure–function relationships. Here, we present a bottom-up approach systematic assembly precise nanoclusters employing strategy that mimics synthetic ease with normally constructed, while producing well-defined covalent nanoscale assemblies topologies. first time, using structurally characterized cluster-based organometallic building block, demonstrate multivalent binding capabilities protein targets.