Regio- and Stereoselective Multisubstituted Enol Ester Synthesis

• DOI: 10.1021/jo201609r
• Publication Date: 2011-09-28T11:38:23Z
• Authors: Noriko Okamoto; Yoshihisa Miwa; Hideki Minami; Kei Takeda; Reiko Yanada
• Keywords: Alkyne

Regio- and stereoselective cohalogenation of alkynes with NXS (X = Br, I) was achieved, the stereoselectivity resulting alkenes dependent on substituent alkyne. Cohalogenation successive cross-coupling gave multisubstituted enol esters in a one-pot process.