Copper-Catalyzed Synthesis of Substituted Quinolines via C–N Coupling/Condensation from ortho-Acylanilines and Alkenyl Iodides

Enamine Ullmann reaction
DOI: 10.1021/jo502630t Publication Date: 2014-12-15T21:21:10Z
ABSTRACT
An efficient cascade copper-catalyzed intermolecular Ullmann-type C–N coupling/enamine condensation reaction is described, in which ortho-acylanilines and alkenyl iodides converted to multisubstituted quinolines good excellent yields.
SUPPLEMENTAL MATERIAL
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