Two New Carbazole Alkaloids from Murraya koenigii

• DOI: 10.1021/np020468a
• Publication Date: 2003-03-28T05:55:40Z
• Authors: Yun-Song Wang; Hong-Ping He; Yue-Mao Shen; Xin Hong; Xiao-Jiang Hao
• Keywords: Carbazole; Murraya

Two new carbazole alkaloids named murrayanine (1) and 8,8' '-biskoenigine (2) were isolated from Murraya koenigii. The structure elucidations for 1 2 carried out on the basis of 1D 2D NMR experiments. Compound was a novel alkaloid with rare phenylpropanyl substitution. symmetrical dimer koenigine showed antiosteoporotic activity in CAT-B model IC50 1.3 μg/mL. synthesis through oxidative coupling using solid state reaction.