Cationic Palladium(II)-Catalyzed Addition of Arylboronic Acids to Nitriles. One-Step Synthesis of Benzofurans from Phenoxyacetonitriles

• DOI: 10.1021/ol062438v
• Publication Date: 2006-11-24T11:08:04Z
• Authors: Baowei Zhao; Xiyan Lu
• Keywords: Cationic polymerization

[Structure: see text] A cationic palladium complex catalyzed addition of arylboronic acids to nitriles yield aryl ketones with moderate good yields was developed. one-step synthesis benzofurans from phenoxyacetonitriles under the catalysis [(bpy)Pd+(micro-OH)]2(-OTf)2 or [(bpy)Pd2+(H2O)2](-OTf)2 developed which showed that catalyst is highly active for these reactions.