Self-Assembly of Cationic, Hetero- or Homonuclear Ruthenium(II) Macrocyclic Rectangles and Their Photophysical, Electrochemical, and Biological Studies

• DOI: 10.1021/om200908c
• Publication Date: 2011-11-14T17:31:33Z
• Authors: Vaishali Vajpayee; Young Ho Song; Yoon Jung Yang; Se Chan Kang; Timothy R. Cook; Dong Wook Kim; Myoung Soo Lah; In Su Kim; Ming Wang; Peter J. Stang; Ki-Whan Chi
• Keywords: Homonuclear molecule; Cationic polymerization; Proton NMR

A series of supramolecular rectangles, including two mixed-metal Ru/Pt complexes, have been formed by the coordination-driven self-assembly a range arene–Ru "molecular clip" acceptors (1a–1d) with rigid dipyridyl-based ligands (2a–2d) over course 10 h in solution. The isolated products were characterized multinuclear NMR (1H and 13C or 31P), HR-ESI-MS, an X-ray diffraction study to support ascribed two-component rectangular structures. rectangles further UV–vis fluorescence studies. redox behaviors 3ca 3da also determined using cyclic voltammetry. Additionally, antitumor activities suite against various human cancer cell lines, significant activity was shown complexes 3ca, 3da, 3cb, 3cc, 3cd, IC50 values as low 2.65 μM.