Recollection and familiarity in amnesic mild cognitive impairment.

• DOI: 10.1037/a0017654
• Publication Date: 2010-05-04T23:38:23Z
• Authors: Laura Serra; Marco Bozzali; Mara Cercignani; Roberta Perri; Lucia Fadda; Carlo Caltagirone; Giovanni A. Carle...
• Keywords: Entorhinal cortex; Memory disorder; Memory Impairment

To investigate whether, in patients with amnesic mild cognitive impairment (a-MCI), recognition deficits are mainly due to a selective of recollection rather than familiarity.Nineteen a-MCI and 23 sex-, age-, education-matched healthy controls underwent two experimental investigations, using the Process Dissociation Procedure (PDP) Remember/Know (R/K) procedure, assess differential contribution familiarity their performance.Both procedures revealed preservation patients. Moreover, R/K procedure showed statistically significant for words that were either read or anagrammed during study phase.A-MCI is known be commonly associated high risk conversion Alzheimer's disease (AD). Several previous studies have demonstrated characteristic episodic memory a-MCI, an early dysfunction recognition. Our findings consistent knowledge neurodegeneration occurring AD, which characterized, at earliest stages, by involvement entorhinal cortex. current supports dual process model recognition, hypothesizes independent processes distinct anatomical substrates.