Relationship between depression, fatigue, subjective cognitive impairment, and objective neuropsychological functioning in patients with multiple sclerosis.

• DOI: 10.1037/a0019222
• Publication Date: 2010-08-30T19:10:25Z
• Authors: Sarah W. Kinsinger; Emily Lattie; David C. Mohr
• Keywords: Depression; Cognitive skill; Neuropsychological Assessment

This study explored the influence of depression and fatigue on subjective cognitive complaints objective neuropsychological impairment in patients with multiple sclerosis (MS).Data for this were taken from a randomized controlled trial, comparing 16 weeks telephone-administered cognitive-behavioral therapy supportive emotion focused treatment depression. The sample includes 127 MS. following self-report measures collected pre- posttreatment: Perceived Deficits Questionnaire, Beck Depression Inventory-II, Modified Fatigue Impact Scale. Measures functioning Hamilton Rating Scale administered over telephone.Our results showed that changes significantly predicted to posttreatment, perceiving fewer problems at posttreatment (beta = .36, p < .001 beta .61, .001, respectively). Changes not related performance. Improvements also improved accuracy abilities (OR .77, OR .90, respectively).The suggest improvements through do performance MS patients, but relate impairment. Furthermore, these improve patients' accurately perceive their functioning.