Clinical outcomes of an integrated treatment for depression and substance use disorders.

• DOI: 10.1037/a0019943
• Publication Date: 2010-09-20T18:56:18Z
• Authors: Katherine P. Lyde...; Susan R. Tate; Kevin M. Cummins; John McQuaid; Eric Granholm; Sandra A. Brown
• Keywords: Pharmacotherapy; Depression; Interpersonal psychotherapy; Substance dependence

The authors compared longitudinal treatment outcomes for depressed substance-dependent veterans (N = 206) assigned to integrated cognitive-behavioral therapy plus standard pharmacotherapy (ICBT + P) or 12-step facilitation (TSF P). Drug and alcohol involvement depressive symptomology were measured at intake 3-month intervals during up 1 year posttreatment. Participants in both conditions showed decreased depression substance use from intake. ICBT P participants maintained improvements over time, whereas TSF had more rapid increases the months following treatment. Decreases symptoms pronounced than 6 Within groups, higher attendance was associated with improved time. Initial levels of a complex predictive relationship long-term outcomes. Early response predicted portion sample. Although treatments depression, may lead stable reductions P.