Identification of a receptor for the morphogen retinoic acid

• DOI: 10.1038/330624a0
• Publication Date: 2003-06-12T21:39:08Z
• Authors: Vincent Giguere; Estelita S. Ong; Prudimar Segui; Ronald M. Evans
• Keywords: Morphogen; Thyroid hormone receptor

Analysis of complementary DNA encoding a novel gene product reveals striking similarity to the steroid and thyroid hormone receptors. Binding and transcription activational studies show it to be a receptor for the vitamin A-related morphogen retinoic acid.