Renal Protective Effects of Aliskiren Beyond Its Antihypertensive Property in a Mouse Model of Progressive Fibrosis

• DOI: 10.1038/ajh.2010.231
• Publication Date: 2010-12-02T15:03:12Z
• Authors: O. Gross; R. Girgert; D. Rubel; J. Temme; S. Theissen; G.-A. Muller
• Keywords: Aliskiren

BackgroundThe direct renin inhibitor aliskiren is known to exhibit a strong antihypertensive effect. However, the organoprotective potential of beyond its properties less clear. This study investigates antifibrotic nephroprotective effects in nonhypertensive mouse model for progressive renal fibrosis.