Self-organization of the human embryo in the absence of maternal tissues

• DOI: 10.1038/ncb3347
• Publication Date: 2016-05-04T17:35:22Z
• Authors: Marta N. Shahbazi; Agnieszka Jedrusik; Sanna Vuoristo; Gaelle Recher; Anna Hupalowska; Virginia Bolton; Norah M. E. Fogarty; Alison Campbell; Liani G. Devito; Dusko Ilic; Yakoub Khalaf; Kathy K. Niakan; Simon Fishel; Magdalena Zernick...
• Keywords: 0301 basic medicine; 570; 610; Gene Expression Regulation, Developmental; Cell Differentiation; Article; Trophoblasts; 03 medical and health sciences; Morphogenesis; Animals; Humans; Cell Lineage; Embryo Implantation; Cells, Cultured; Yolk Sac

(Abstracted from Nat Cell Biol 2016;18:700–708) The failure of an embryo to implant into the womb is a major cause of early pregnancy loss. The human embryo must implant into the uterus on the seventh day of development to survive and to develop further.