Estimating the potential public health impact of seasonal malaria chemoprevention in African children

• DOI: 10.1038/ncomms1879
• Publication Date: 2012-06-06T09:55:07Z
• Authors: Matthew Cairns; Arantxa Roca-Feltrer; Tini Garske; Anne L. Wilson; Diadier Diallo; Paul J. Milligan; Azra C Ghani; Brian M. Greenwood
• Keywords: Seasonality

Seasonal malaria chemoprevention, previously known as intermittent preventive treatment in children, is highly effective areas with a short transmission season. Here we assess seasonality incidence data and define predictor of based on rainfall. We then use spatial rainfall, endemicity population to identify likely have seasonal incidence, estimate the at risk burden where chemoprevention would be appropriate. that suitable for there are 39 million children under 5 years age, who experience 33.7 episodes 152,000 childhood deaths from each year. The majority this occurs Sahelian or sub-Sahelian regions Africa. Our suggest has potential avert several cases tens thousands year if successfully delivered populations risk. can lower periodical. Combining endemicity, Cairnset al. geographical sub-Saharan Africa intervention cost-effective.