Effect of anthelmintic treatment on leptin, adiponectin and leptin to adiponectin ratio: a randomized-controlled trial
Resistin
DOI:
10.1038/nutd.2017.37
Publication Date:
2019-05-23T13:26:36Z
AUTHORS (13)
ABSTRACT
Abstract Emerging evidence suggests that helminths might confer protection against the development of type 2 diabetes. We aimed to assess role adipokines in mediating effect on insulin resistance. Serum samples were obtained from a randomized-controlled trial anthelmintic treatment an area endemic for soil-transmitted (STH), Flores Island, Indonesia. In STH-infected subjects, significantly increased ratio leptin adiponectin (treatment factor (95% confidence interval (CI)), P -value interaction: 1.20 (1.06–1.35), =0.010), which largely stemmed significant reduction (0.91 (0.85–0.98), =0.020) and trend increase level (1.10 (1.00–1.21), =0.119). No resistin was observed. This seemed contribute observed deworming resistance (IR) as adjustment attenuated IR 1.07 (1.01–1.14, =0.023) 1.05 (0.99–1.11, =0.075). Anthelmintic subjects increases may small part modest IR. Further studies will be needed changes adipokine levels host immune response metabolism.
SUPPLEMENTAL MATERIAL
Coming soon ....
REFERENCES (20)
CITATIONS (13)
EXTERNAL LINKS
PlumX Metrics
RECOMMENDATIONS
FAIR ASSESSMENT
Coming soon ....
JUPYTER LAB
Coming soon ....