Age-specific seroprevalence of human polyomavirus 12 and Saint Louis and New Jersey polyomaviruses

• DOI: 10.1038/s41426-018-0026-0
• Publication Date: 2018-03-05T09:52:12Z
• Authors: Pauline Gaboriaud; Marion Ferté; Françoise Arnold; Valérie Leblond; Jérôme Nicol; Heloïse Debare; Mélanie Le Meur; Fernanda Martini; Mauro Tognon; Antoine Touzé
• Keywords: Adult; Male; Adolescent; Virologie; polyomavirus; Enzyme-Linked Immunosorbent Assay; Antibodies, Viral; Article; Young Adult; 03 medical and health sciences; Seroepidemiologic Studies; Virology; Humans; HPyV, Antibody, Infection; Child; technique elisa; Aged; [SDV.MP.VIR] Life Sciences [q-bio]/Microbiology and Parasitology/Virology; Aged, 80 and over; Polyomavirus Infections; 0303 health sciences; Infant; Middle Aged; 3. Good health; Italy; Child, Preschool; [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology; anticorps; Female; humain; Polyomavirus

The presence of specific antibodies against human polyomavirus 12, Saint Louis polyomavirus and New Jersey polyomavirus was investigated by using virus-like particle-based ELISAs with serum samples from 706 Italians aged 1- to 100-years-old. The findings indicate that these polyomaviruses circulate widely in humans, with peak seroprevalence, observed at adulthood, of 97.3%, 93.3%, 57.5%, for human polyomavirus 12, Saint Louis polyomavirus and New Jersey polyomavirus, respectively.