Spontaneous buckling of contractile poroelastic actomyosin sheets

• DOI: 10.1038/s41467-018-04829-x
• Publication Date: 2018-06-19T11:16:18Z
• Authors: Y. Ideses; V. Erukhimovitch; R. Brand; D. Jourdain; J. Salmeron Herna...; U. R. Gabinet; S. A. Safran; K. Kruse; A. Bernheim-Grosw...
• Keywords: Contractility; Poromechanics; Elasticity

Shape transitions in developing organisms can be driven by active stresses, notably, contractility generated myosin motors. The mechanisms generating tissue folding are typically studied epithelia. There, the interaction between cells is also coupled to an elastic substrate, presenting a major difficulty for studying contraction induced folding. Here we study and buckling of active, initially homogeneous, thin actomyosin networks isolated from bounding surfaces. network behaves as poroelastic material, where flow fluid during contraction. Contraction starts at system boundaries, proceeds into bulk, eventually leads spontaneous sheet periphery. instability resulted self-organization emergence density gradients contractility. wavelength increases linearly with thickness. Our offers well-controlled way mechanically induced, shape matter.