A TaSnRK1α-TaCAT2 model mediates resistance to Fusarium crown rot by scavenging ROS in common wheat

• DOI: 10.1038/s41467-025-57936-x
• Publication Date: 2025-03-15T11:08:04Z
• Authors: Xia Yang; Leilei Zhang; Jiajie Wei; Lexin Liu; Di Liu; Xiangning Yan; Minjie Yuan; Lingran Zhang; Ning Zhang; Yan Ren; Feng Chen

Fusarium crown rot (FCR) is a serious underlying disease to threaten wheat yield and quality recently. Here, we identify catalase antioxidant enzyme (TaCAT2) through genome wide association study (GWAS) whole-exome sequencing (WES) in two nested bi-parental populations. We verify the function of TaCAT2 regulating FCR resistance by genetic transformation. Moreover, screen sucrose non-fermenting-1-related protein kinase alpha subunit (TaSnRK1α) interacting with TaCAT2, subsequently find that TaSnRK1α phosphorylates TaCAT2. next an FCR-resistance haplotype TaCAT2Ser214, confirm Ser214 key phosphorylation site for TaSnRK1α. also results higher accumulation TaCAT2Ser214 than TaCAT2Thr214, which possibly contribute scavenging ROS (reactive oxygen species) plants. Furthermore, verified Taken together, propose TaSnRK1α-TaCAT2 model mediate threatens yields. authors report roles mediating reactive species