Scallop genome provides insights into evolution of bilaterian karyotype and development

• DOI: 10.1038/s41559-017-0120
• Publication Date: 2017-04-03T20:26:13Z
• Authors: Shi Wang; Jinbo Zhang; Wenqian Jiao; Ji Li; Xiaogang Xun; Yan Sun; Ximing Guo; Pin Huan; Bo Dong; Lingling Zhang; Xiaoli Hu; Xiaoqing Sun; Jing Wang; Chengtian Zhao; Yangfan Wang; Dawei Wang; Xiaoting Huang; Ruijia Wang; Jia Lv; Yuli Li; Zhifeng Zhang; Baozhong Liu; Wei Lu; Yuanyuan Hui; Jun Liang; Zunchun Zhou; Rui Hou; Xue Li; Yunchao Liu; Hengde Li; Xianhui Ning; Yu Lin; Liang Zhao; Qiang Xing; Jinzhuang Dou; Yangping Li; Junxia Mao; Haobing Guo; Huaiqian Dou; Tianqi Li; Chuang Mu; Wenkai Jiang; Qiang Fu; Xiaoteng Fu; Yan Miao; Jian Liu; Qian Yu; Ruojiao Li; Huan Liao; Xuan Li; Yifan Kong; Zhi Jiang; Daniel Chourrout; Ruiqiang Li; Zhenmin Bao
• Keywords: 0301 basic medicine; 03 medical and health sciences; Article

Abstract Reconstructing the genomes of bilaterian ancestors is central to our understanding animal evolution, where knowledge from ancient and/or slow-evolving lineages critical. Here we report a high-quality, chromosome-anchored reference genome for scallop Patinopecten yessoensis , bivalve mollusc that has with many ancestral features. Chromosome-based macrosynteny analysis reveals striking correspondence between 19 chromosomes and 17 presumed linkage groups at level conservation previously unseen, suggesting may have karyotype close ancestor. Scallop Hox gene expression follows new mode subcluster temporal co-linearity possibly provide great potential in supporting diverse body plans. Transcriptome mantle eyes finds unexpected diversity phototransduction cascades potentially Pax2/5/8 -dependent pathway noncephalic eyes. The outstanding preservation developmental control makes valuable resource early evolution biology.