Genome sequence of the progenitor of wheat A subgenome Triticum urartu

• DOI: 10.1038/s41586-018-0108-0
• Publication Date: 2018-05-08T15:59:10Z
• Authors: Hong-Qing Ling; Bin Ma; Xiaoli Shi; Hui Liu; Lingli Dong; Hua Sun; Yinghao Cao; Qiang Gao; Shusong Zheng; Ye Li; Ying Yu; Huilong Du; Ming Qi; Yan Li; Hongwei Lu; Hua Yu; Yan Cui; Ning Wang; Chunlin Chen; Huilan Wu; Yan Zhao; Juncheng Zhang; Yiwen Li; Wenjuan Zhou; Bairu Zhang; Weijuan Hu; Michiel J. T. van...; Jifeng Tang; Hanneke M. A. Wit...; Shancen Zhao; Zhensheng Li; Aimin Zhang; Daowen Wang; Chengzhi Liang
• Keywords: Polyploid; Comparative Genomics

Triticum urartu (diploid, AA) is the progenitor of A subgenome tetraploid (Triticum turgidum, AABB) and hexaploid aestivum, AABBDD) wheat1,2. Genomic studies T. have been useful for investigating structure, function evolution polyploid wheat genomes. Here we report generation a high-quality genome sequence by combining bacterial artificial chromosome (BAC)-by-BAC sequencing, single molecule real-time whole-genome shotgun sequencing3, linked reads optical mapping4,5. We assembled seven chromosome-scale pseudomolecules identified protein-coding genes, suggest model chromosomes. Comparative analyses with genomes other grasses showed gene loss amplification in numbers transposable elements genome. Population genomics analysis 147 accessions from across Fertile Crescent clustering three groups, differences altitude biostress, such as powdery mildew disease. The assembly provides valuable resource studying genetic variation related grasses, promises to facilitate discovery genes that could be improvement. urartu, wheat, insight into duplication during grass evolution.