In vitro cytotoxicity activity of novel Schiff base ligand–lanthanide complexes

• DOI: 10.1038/s41598-018-21366-1
• Publication Date: 2018-02-08T16:00:47Z
• Authors: Kavitha Andiappan; Anandhavelu Sanmugam; Easwaramoorthy De...; K. Karuppasamy; Hyun-Seok Kim; Dhanasekaran Vikr...
• Keywords: HeLa

A Schiff base ligand (SBL), N2, N3-bis (anthracen-9-ylmethylene) pyridine-2, 3-diamine, was synthesized through the condensation of 2,6-diaminopyridine and anthracene-9-carbaldehyde using a 1:2 ratio. 1H NMR spectra confirmed observation non-involvement aromatic carboxylic proton in SBL. novel series lanthanide (i.e., praseodymium (Pr), erbium (Er), ytterbium (Yb))-based SBL metal complexes successfully synthesized, their functional groups were elaborately demonstrated UV-visible, Fourier transform infrared (FT-IR), fluorescence spectroscopy analyses. FT-IR spectral studies revealed that behaved as bidentate it structured with ions by two azomethine nitrogens. The SBL-based performed for cytotoxicity activity versus Vero, human breast cancer (MCF7), cervical (HeLa) anticancer cell lines.