A case control study of occupation and cardiovascular disease risk in Japanese men and women

• DOI: 10.1038/s41598-021-03410-9
• Publication Date: 2021-12-14T11:03:55Z
• Authors: Kota Fukai; Yuko Furuya; Shoko Nakazawa; Noriko Kojimahara; Keika Hoshi; Akihiro Toyota; Masayuki Tatemichi
• Keywords: Stroke

Abstract We aimed to investigate the risks of cardiovascular diseases associated with specific occupations, using a nation-wide, multicentre, hospital-based registry data from Inpatient Clinico-Occupational Survey. The analysis included 539,110 controls (non-circulatory disease) and 23,792 cases (cerebral infarction, intracerebral/subarachnoid hemorrhage, acute myocardial infarction) aged ≥ 20 years who were initially hospitalized during 2005–2015. participants’ occupational clinical histories collected by interviewers medical doctors. Occupations coded into 81 categories according Japanese standard occupation classification. Multivariable logistic regression adjusted for age, admission year hospital, smoking, alcohol consumption, hypertension, shift-work was conducted sex general clerical workers as reference. Increased cerebral intracerebral subarachnoid observed in 15, 20, 25, 1 occupation(s) men, 9, 2, 10 occupations women. Motor vehicle drivers, food drink preparatory workers, fishery cargo civil engineer other manual men women faced increased all three stroke subtypes. Our findings demonstrate associations between risk disease incidence suggest that may vary occupation.