Wiskott Aldrich syndrome: healthcare utilizations and disparities in transplant care

• DOI: 10.1038/s41598-021-84328-0
• Publication Date: 2021-02-25T11:04:11Z
• Authors: Nikki Agarwal; Divyaswathi Citla...; Sindhoosha Malay; Nirav Patil; Anjali Shekar; Sanjay Ahuja; Jignesh Dalal
• Keywords: Wiskott–Aldrich syndrome

Wiskott Aldrich syndrome (WAS) is a rare disease and hematopoietic stem cell transplant (HCT) considered the treatment modality of choice for WAS. We conducted cross-sectional analysis on KIDS' pediatric inpatient database compared hospitalization rates, complications healthcare utilizations in non-transplant arms. Of 383 admissions with diagnosis WAS between 2006-2012, 114 underwent 269 did not. The arm included older children, female patients more African Americans. Death income payer source were similar both arms, however total charge each admission was higher arm. Emergency room visits but non-elective Length stay prolonged When comparing morbidities, lymphomas, ulcerative colitis autoimmune seen only Our study shows that largest contributor to utilization patients. identified disparities based race socioeconomic status found this being appropriately directed centers HCT expertise. noted change practice moving away from splenectomy