An open science resource for establishing reliability and reproducibility in functional connectomics

• DOI: 10.1038/sdata.2014.49
• Publication Date: 2014-12-08T13:11:13Z
• Authors: Xi-Nian Zuo; Jeffrey S Anderson; Pierre Bellec; Rasmus M Birn; Bharat B Biswal; Janusch Blautzik; John C.S Breitner; Randy L Buckner; Vince D Calhoun; F. Xavier Castell...; Antao Chen; Bing Chen; Jiangtao Chen; Xu Chen; Stanley J Colcombe; William Courtney; R Cameron Craddock; Adriana Di Martino; Hao-Ming Dong; Xiaolan Fu; Qiyong Gong; Krzysztof J Gorgo...; Ying Han; Ye He; Yong He; Erica Ho; Avram Holmes; Xiao-Hui Hou; Jeremy Huckins; Tianzi Jiang; Yi Jiang; William Kelley; Clare Kelly; Margaret King; Stephen M LaConte; Janet E Lainhart; Xu Lei; Hui-Jie Li; Kaiming Li; Kuncheng Li; Qixiang Lin; Dongqiang Liu; Jia Liu; Xun Liu; Yijun Liu; Guangming Lu; Jie Lu; Beatriz Luna; Jing Luo; Daniel Lurie; Ying Mao; Daniel S Margulies; Andrew R Mayer; Thomas Meindl; Mary E Meyerand; Weizhi Nan; Jared A Nielsen; David O’Connor; David Paulsen; Vivek Prabhakaran; Zhigang Qi; Jiang Qiu; Chunhong Shao; Zarrar Shehzad; Weijun Tang; Arno Villringer; Huiling Wang; Kai Wang; Dongtao Wei; Gao-Xia Wei; Xu-Chu Weng; Xuehai Wu; Ting Xu; Ning Yang; Zhi Yang; Yu-Feng Zang; Lei Zhang; Qinglin Zhang; Zhe Zhang; Zhiqiang Zhang; Ke Zhao; Zonglei Zhen; Yuan Zhou; Xing-Ting Zhu; Michael P Milham
• Keywords: Connectomics; Open Science

Abstract Efforts to identify meaningful functional imaging-based biomarkers are limited by the ability reliably characterize inter-individual differences in human brain function. Although a growing number of connectomics-based measures reported have moderate high test-retest reliability, variability data acquisition, experimental designs, and analytic methods precludes generalize results. The Consortium for Reliability Reproducibility (CoRR) is working address this challenge establish reliability as minimum standard development connectomics. Specifically, CoRR has aggregated 1,629 typical individuals’ resting state fMRI (rfMRI) (5,093 rfMRI scans) from 18 international sites, openly sharing them via International Data-sharing Neuroimaging Initiative (INDI). To allow researchers generate various estimates reproducibility, variety acquisition procedures designs included. Similarly, enable users assess impact commonly encountered artifacts (for example, motion) on characterizations variation, datasets varying quality