Zinc status and taste acuity in older Europeans: the ZENITH study

• DOI: 10.1038/sj.ejcn.1602295
• Publication Date: 2005-10-28T11:27:01Z
• Authors: B J Stewart-Knox; E E A Simpson; H Parr; G Rae; A Polito; F Intorre; N Meunier; M Andriollo-Sanchez; J M O'Connor; C Coudray; J J Strain
• Keywords: Aged, 80 and over; Male; Aging; Analysis of Variance; 0303 health sciences; Erythrocytes; Signal Detection, Psychological; Age Factors; Nutritional Status; Middle Aged; Nutrition Surveys; Europe; Zinc; 03 medical and health sciences; ROC Curve; Reference Values; Taste; Humans; Female; Single-Blind Method; Aged

Age-related decline in taste acuity may be both a cause and an effect of depleted zinc and/or increased zinc requirement.The aim of this study was to explore associations between zinc status and taste acuity in healthy older European adults aged 55-90 y.Volunteers were recruited within Italy (n = 108 aged 70-90 y), the United Kingdom (UK) (n = 93 aged 55-70) and two regions of France (n = 186), Grenoble (aged 70-90 y) and Clermont-Ferrand (aged 55-70 y).A signal detection theory approach was adopted, employing a three-alternative, forced-choice procedure. The data were converted to R-indices and bivariate correlations were computed to explore relationships between serum zinc, erythrocyte zinc and taste acuity. ANOVA was undertaken to determine regional differences in zinc status.Higher erythrocyte zinc status was associated with better acuity for salt (sodium chloride) taste in the sample as a whole (P = 0.012) (n = 385). Higher serum zinc levels were associated with greater sensitivity to sour taste (citric acid) (P = 0.015) only in the older groups (aged 70-90 y). There were no apparent associations between serum or erythrocyte zinc status and acuity for bitter (quinine) or sweet (sucrose) tastes irrespective of age.These results agree with those previously suggesting that age-related detriment in sensitivity for salt taste may be associated with depleted zinc.