Endovascular Electrodes for Electrical Stimulation of Blood Vessels for Vasoconstriction – a Finite Element Simulation Study

• DOI: 10.1038/srep31507
• Publication Date: 2016-08-18T09:15:35Z
• Authors: Noa Kezurer; Nairouz Farah; Yossi Mandel
• Keywords: Multiphysics

Hemorrhagic shock accounts for 30-40 percent of trauma mortality, as bleeding may sometimes be hard to control. Application short electrical pulses on blood vessels was recently shown elicit robust vasoconstriction and reduction loss following vascular injury. In this study we present a novel approach based endovascular application situations where access the vessel is limited. addition ease access, hypothesize that will result in localized efficient vasoconstriction. Using computer modeling (COMSOL Multiphysics, Electric Currents Module), studied effect pulsed treatment abdominal aorta pigs, compared efficiency different electrodes configurations electric field amplitude, homogeneity locality when applied wall. Results reveal optimal configuration four are used, spaced 13 mm apart. Furthermore, temperature investigations (bio-heat model, COMSOL Multiphysics) show maximum expected rise 1.2 degrees; highlighting safety configuration. These results can aid planning an safe approach.