Genome-wide association study for performance traits in chickens using genotype by sequencing approach

• DOI: 10.1038/srep41748
• Publication Date: 2017-02-09T10:23:28Z
• Authors: Fábio Pértille; Gabriel Costa Mon...; Ricardo Zanella; José de Ribamar d...; Clarissa Boschiero; Gregori Alberto R...; Gerson Barreto Mo...; Mônica Corrêa Ledur; Luiz Lehmann Cout...
• Keywords: Genome-wide Association Study; Genetic Association; Association (psychology)

Performance traits are economically important and targets for selection in breeding programs, especially the poultry industry. To identify regions on chicken genome associated with performance traits, different genomic approaches have been applied last years. The aim of this study was application CornellGBS approach (134,528 SNPs generated from a PstI restriction enzyme) Genome-Wide Association Studies (GWAS) an outbred F2 population. We validated 91.7% these 134,528 after imputation missed genotypes. Out those, 20 were feed conversion, one body weight at 35 days age (P < 7.86E-07) 93 suggestively variety 1.57E-05). majority (86.2%) overlapped previously mapped QTL same some also showed novel potential regions. results obtained suggests future searches candidate genes refinements as well use described here programs.