Vasopressin modulates social recognition-related activity in the left temporoparietal junction in humans

Temporoparietal junction Prosocial Behavior Social Isolation
DOI: 10.1038/tp.2011.2 Publication Date: 2011-04-04T12:54:50Z
ABSTRACT
The neuropeptide vasopressin is a key molecular mediator of social behavior in animals and humans, implicated anxiety autism. Social recognition, the ability to assess familiarity others, essential for appropriate interactions enhanced by vasopressin; however, neural mechanisms mediating this effect humans are unknown. Using functional magnetic resonance imaging (fMRI) an implicit recognition matching task, we employed double-blinded procedure which 20 healthy male volunteers self-administered 40 UI or placebo intranasally, 45 min before performing task scanner. In random-effects fMRI analysis, show that induces regionally specific alteration node theory mind network, left temporoparietal junction, identifying neurobiological mechanism prosocial effects suggests novel treatment strategies.
SUPPLEMENTAL MATERIAL
Coming soon ....
REFERENCES (26)
CITATIONS (55)