A novel physiologic sampling pump capable of rapid response to breathing

• DOI: 10.1039/b816699d
• Publication Date: 2009-03-04T09:35:42Z
• Authors: Larry Lee; Michael Flemmer; Eun Gyung Lee; Martin Harper; Ming-I Lin; William Groves; Andris Freivalds; James Slaven
• Keywords: Air Pollutants; 03 medical and health sciences; 0302 clinical medicine; Occupational Exposure; Respiration; Humans; Environmental Monitoring

The merits of using physiologic sampling pumps (PSPs) instead constant-flow pumps, i.e., "traditional pumps" (TSPs), are discussed. A novel PSP that overcomes shortcomings previous designs is presented. Calibrated valves used to obviate pump inertia has limited the system response and accuracy prior work. Technologies provide minute ventilation (V[combining dot above](E)) subjects in real time may therefore be limit their own accuracies sample inhalation exposures. Analysis design data from a prototype presented show how air can modulated follow breathing.