Overcoming the PEG-addiction: well-defined alternatives to PEG, from structure–property relationships to better defined therapeutics

• DOI: 10.1039/c0py00406e
• Publication Date: 2011-03-28T12:00:22Z
• Authors: Matthias Barz; Robert Luxenhofer; Rudolf Zentel; María J. Vicent
• Keywords: 01 natural sciences; 0104 chemical sciences

Synthetic methods in polymer chemistry have evolved tremendously during the last decade. Nowadays more and attention is devoted to application of those tools development next generation nanomedicines. Nevertheless, poly(ethylene glycol) (PEG) remains most frequently used for biomedical applications. In this review, we try summarize recent efforts developments controlled polymerisation techniques that may allow alternatives PEG based systems can be improve properties future therapeutics.