Ruthenium(ii) polypyridyl complexes as carriers for DNA delivery

• DOI: 10.1039/c1cc13863d
• Publication Date: 2011-09-06T15:00:44Z
• Authors: Satish S. Bhat; Avinash S. Kumbhar; Anupa A. Kumbhar; Ayesha Khan; Peter Lönnecke; Evamarie Hey-Hawkins
• Keywords: DNA condensation

Two novel water soluble ruthenium(II) complexes [Ru(bpy)2(bqbg)]2+ and [Ru(phen)2(bqbg)]2+ have been structurally characterized their DNA condensation activity, cytotoxicity, cellular uptake studies of condensates as potential non-viral carriers were evaluated.