Simultaneous testing of multiclass organic contaminants in food and environment by liquid chromatography/dielectric barrier discharge ionization-mass spectrometry

• DOI: 10.1039/c2an35705d
• Publication Date: 2012-09-12T09:03:09Z
• Authors: Bienvenida Gilber...; Juan F. García-Reyes; Cordula Meyer; Antje Michels; Joachim Franzke; Antonio Molina-Díaz; Heiko Hayen
• Keywords: Atmospheric-pressure chemical ionization; Orbitrap; Ambient ionization

A Dielectric Barrier Discharge Ionization (DBDI) LC/MS interface is based on the use of a low-temperature helium plasma, which features possibility simultaneous ionization species with wide variety physicochemical properties. In this work, performance LC/DBDI-MS for trace analysis highly relevant in food and environment has been examined. Over 75 including multiclass priority organic contaminants residues such as pesticides, polycyclic aromatic hydrocarbons, organochlorine species, pharmaceuticals, personal care products, drugs abuse were tested. application was assessed compared standard sources (electrospray (ESI) atmospheric pressure chemical (APCI)). The used benchtop Orbitrap mass spectrometer 10 Hz polarity switching mode, so that both positive negative ion mode acquisitions are possible acquisition cycles matching requirements fast liquid chromatography. Both polar nonpolar (including those typically analyzed by GC/electron ionization-MS) can be tested single run using mode. methodology found to effective detecting array compounds at concentration levels low ng L−1 μg kg−1 range wastewater matrices, respectively. linearity evaluated an olive oil extract, obtaining good correlation coefficients studied range. Additionally, minor matrix effects (≤15% signal suppression or enhancement) observed most analytes complex fatty matrix. results obtained data from ESI APCI sources, merged coverage between terms analyte higher overall sensitivity proposed source DBD principle. approach further extends current methods towards even larger (non-ESI amenable) may find several applications fields testing metabolomics where GC/MS combined cover many different possible.